Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894733 | 0.93 | ALDH1A1 (0.36) | TSHRALDH1A1LMNAPRKCA | |
| SCHEMBL14666170 | 0.88 | TSHR (0.39) | TSHRALDH1A1LMNAPRKCA | |
| SCHEMBL11920352 | 0.86 | TSHR (0.44) | TSHRALDH1A1PRKCA | |
| SCHEMBL15894728 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAPRKCA | |
| SCHEMBL890783 | 0.84 | TSHR (0.50) | TSHRALDH1A1LMNAPRKCA | |
| SCHEMBL18030871 | 0.82 | TSHR (0.31) | TSHRALDH1A1LMNA | |
| SCHEMBL22417596 | 0.81 | TSHR (0.40) | TSHRPRKCA | |
| SCHEMBL19865461 | 0.81 | TSHR (0.35) | TSHR | |
| SCHEMBL15894729 | 0.81 | TSHR (0.44) | TSHRALDH1A1PRKCA | |
| SCHEMBL14729529 | 0.80 | TSHR (0.36) | TSHRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033345-A1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | 3M INNOVATIVE PROPERTIES COMPANY | 2022-02-03 | — | — | US | disclosed |
| US-9907733-B2 | Dental compositions comprising addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-06 | — | — | US | disclosed |
| US-9907733-B2 | Dental compositions comprising addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| EP-2748206-B1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2015-09-16 | — | — | EP | disclosed |
| US-8980969-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980969-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140206788-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206788-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2013028397-A2 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013028401-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033345-A1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | PARP1, ETFA, PARP2 | TSHR 3927/4885ALDH1A1 732/4885LMNA 33/4885 |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | RAD51, TUBA8, ERCC4 | TSHR 4850/4885ALDH1A1 2749/4885LMNA 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.