Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6128110 | 0.94 | RBP4 (0.36) | DPP4DPP8DPP7DPP9RBP4 | |
| SCHEMBL14723477 | 0.94 | RBP4 (0.36) | DPP4DPP8DPP7DPP9RBP4 | |
| SCHEMBL14723221 | 0.91 | NR1H2 (0.40) | DPP4DPP8DPP7DPP9KDM1A | |
| SCHEMBL14730330 | 0.91 | NR1H2 (0.40) | DPP4DPP8DPP7DPP9KDM1A | |
| SCHEMBL6128115 | 0.90 | NTRK1 (0.41) | DPP4RBP4KDM1ANR1H2RET | |
| SCHEMBL14722979 | 0.90 | NTRK1 (0.41) | DPP4RBP4KDM1ANR1H2RET | |
| SCHEMBL14722985 | 0.88 | RBP4 (0.45) | RBP4KDM1AMAOBEIF2AK4CKS1B | |
| SCHEMBL14723098 | 0.85 | NR1H2 (0.38) | DPP4DPP8DPP7DPP9KDM1A | |
| SCHEMBL14730264 | 0.85 | HPGDS (0.38) | DPP4DPP8DPP7DPP9KDM1A | |
| SCHEMBL6128140 | 0.83 | GPR119 (0.36) | DPP4DPP8DPP7DPP9NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |