Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730347 | 0.84 | NTRK1 (0.36) | MCHR1DPP4KCNH2KIF11VNN1 | |
| SCHEMBL14730188 | 0.71 | DPP4 (0.50) | MCHR1DPP4KCNH2DPP9DPP8 | |
| SCHEMBL14730184 | 0.70 | GPR119 (0.36) | MCHR1DPP4KCNH2DPP9DPP8 | |
| SCHEMBL14730299 | 0.70 | DPP4 (0.37) | MCHR1DPP4KCNH2DPP9DPP8 | |
| SCHEMBL14730345 | 0.70 | NTRK1 (0.40) | MCHR1VNN1 | |
| SCHEMBL14730287 | 0.70 | ALOX5AP (0.37) | MCHR1DPP4DPP9DPP8VNN1 | |
| SCHEMBL14730289 | 0.68 | MCHR1 (0.34) | MCHR1DPP4KCNH2DPP9DPP8 | |
| SCHEMBL470520 | 0.67 | DPP4 (0.42) | MCHR1DPP4KCNH2DPP9DPP8 | |
| SCHEMBL470572 | 0.66 | MCHR1 (0.51) | MCHR1DPP4KCNH2DPP9DPP8 | |
| SCHEMBL28646233 | 0.66 | CCR5 (0.51) | MCHR1KCNH2KIF11VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |