Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168148 | 0.76 | ALDH1A1 (0.41) | METAP2METAP1KMT2ALMNAMAPT | |
| SCHEMBL3182595 | 0.76 | METAP2 (0.40) | METAP2METAP1KMT2AMAPTTDP1 | |
| SCHEMBL3173557 | 0.70 | RAB9A (0.38) | METAP2METAP1KMT2ALMNAMAPT | |
| SCHEMBL3173555 | 0.70 | RAB9A (0.38) | METAP2METAP1KMT2ALMNAMAPT | |
| SCHEMBL13530344 | 0.68 | MAPK14 (0.39) | METAP2METAP1LMNATDP1ALDH1A1 | |
| SCHEMBL14730588 | 0.67 | METAP2 (0.35) | METAP2METAP1MAPTTDP1ALDH1A1 | |
| SCHEMBL13530376 | 0.66 | P2RY12 (0.43) | KMT2ALMNAKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL13530363 | 0.64 | HTT (0.45) | LMNATDP1NFE2L2HTT | |
| SCHEMBL13530302 | 0.64 | TDP1 (0.39) | KMT2AMAPTTDP1NFE2L2KDM4E | |
| SCHEMBL27651022 | 0.63 | METAP2 (0.43) | METAP2METAP1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562161-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |