Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173557 | 0.83 | RAB9A (0.38) | METAP2METAP1ALDH1A1TDP1MAPT | |
| SCHEMBL3173555 | 0.83 | RAB9A (0.38) | METAP2METAP1ALDH1A1TDP1MAPT | |
| SCHEMBL17011494 | 0.76 | KEAP1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL3182595 | 0.75 | METAP2 (0.40) | METAP2METAP1ALDH1A1TDP1MAPT | |
| SCHEMBL17011470 | 0.75 | HTT (0.35) | ALDH1A1TDP1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL13530489 | 0.73 | LMNA (0.40) | ALDH1A1MAPT | |
| SCHEMBL13530344 | 0.72 | MAPK14 (0.39) | METAP2METAP1ALDH1A1TDP1KDM4E | |
| SCHEMBL13529895 | 0.72 | MAPT (0.39) | ALDH1A1TDP1MAPTNPC1RAB9A | |
| SCHEMBL13529770 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1TDP1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3168148 | 0.68 | ALDH1A1 (0.41) | METAP2METAP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562161-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |