Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731139 | 0.99 | TGFBR1 (0.41) | TGFBR1LMNAKMT2AMAPTNPSR1 | |
| SCHEMBL14731042 | 0.97 | TGFBR1 (0.41) | TGFBR1LMNAKMT2AMAPTNPSR1 | |
| SCHEMBL14731124 | 0.87 | MAPT (0.43) | LMNAKMT2AMAPTNPSR1HTT | |
| SCHEMBL14731120 | 0.86 | MAPT (0.44) | LMNAKMT2AMAPTNPSR1HTT | |
| SCHEMBL14731125 | 0.86 | LMNA (0.43) | TGFBR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL14731035 | 0.85 | ALDH1A1 (0.40) | TGFBR1LMNAMAPTNPSR1HTT | |
| SCHEMBL14731044 | 0.85 | MAPT (0.38) | TGFBR1LMNAKMT2AMAPTNPSR1 | |
| SCHEMBL14722704 | 0.84 | LMNA (0.44) | TGFBR1LMNAMAPTKDM4ECCR1 | |
| SCHEMBL14731061 | 0.84 | ALDH1A1 (0.40) | TGFBR1LMNAMAPTNPSR1HTT | |
| SCHEMBL14731034 | 0.83 | MAPT (0.38) | TGFBR1LMNAKMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026900-A1 | PYRIDINE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |