Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731125 | 0.99 | LMNA (0.43) | LMNAL3MBTL1CCR1CCR8HRH2 | |
| SCHEMBL14731126 | 0.97 | LMNA (0.41) | LMNAL3MBTL1CCR1CCR8HRH2 | |
| SCHEMBL14731024 | 0.91 | THRB (0.44) | CCR1CCR8HRH2HRH3HTR2A | |
| SCHEMBL14731127 | 0.90 | THRB (0.44) | CCR1CCR8HRH2HRH3HTR2A | |
| SCHEMBL14731023 | 0.88 | HTR2A (0.45) | CCR1CCR8HRH2HRH3HTR2A | |
| SCHEMBL14731120 | 0.88 | MAPT (0.44) | LMNAL3MBTL1CCR1CCR8MAPT | |
| SCHEMBL14731033 | 0.88 | TGFBR1 (0.46) | LMNACCR1CCR8HRH2HRH3 | |
| SCHEMBL14731015 | 0.88 | THRB (0.44) | CCR1CCR8HRH2HRH3HTR2A | |
| SCHEMBL14731036 | 0.87 | TGFBR1 (0.46) | LMNACCR1CCR8HRH2HRH3 | |
| SCHEMBL14731137 | 0.87 | HTR2A (0.44) | CCR1CCR8HRH2HRH3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026900-A1 | PYRIDINE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026900-A1 | PYRIDINE DERIVATIVES AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |