Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732011 | 0.84 | NPC1 (0.31) | — | |
| SCHEMBL8416356 | 0.83 | HSD11B1 (0.42) | ARPDK2HSD11B1CYP2A6 | |
| SCHEMBL14732006 | 0.80 | PTPN5 (0.36) | ARPDK2HSD11B1 | |
| SCHEMBL5528999 | 0.77 | NPC1 (0.39) | HSD11B1CYP2A6 | |
| SCHEMBL6682355 | 0.74 | CYP2A6 (0.40) | HSD11B1CYP2A6 | |
| SCHEMBL9138237 | 0.72 | HSD11B1 (0.41) | HSD11B1CYP2A6 | |
| SCHEMBL14732027 | 0.69 | CYP2A6 (0.37) | CYP2A6 | |
| SCHEMBL3220922 | 0.68 | — | — | |
| SCHEMBL7839044 | 0.68 | PLA2G7 (0.40) | HSD11B1CYP2A6 | |
| SCHEMBL7465625 | 0.67 | CYP2A6 (0.50) | HSD11B1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |