Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528999 | 0.83 | NPC1 (0.39) | HSD11B1CYP2A6TP53 | |
| SCHEMBL14732007 | 0.83 | AR (0.31) | HSD11B1ARCYP2A6PDK2 | |
| SCHEMBL2432403 | 0.81 | GPR3 (0.41) | HSD11B1PDE2APDE10AMAT2AGPR3 | |
| SCHEMBL5778162 | 0.81 | HSD11B1 (0.38) | HSD11B1ARGPR3 | |
| SCHEMBL6682355 | 0.80 | CYP2A6 (0.40) | HSD11B1STK10SLKGPR3CYP2A6 | |
| SCHEMBL5323119 | 0.78 | CYP1A1 (0.39) | GPR3 | |
| SCHEMBL9138237 | 0.77 | HSD11B1 (0.41) | HSD11B1PDE2APDE10ASTK10SLK | |
| SCHEMBL4439285 | 0.77 | PDE2A (0.39) | PDE2AMCL1 | |
| SCHEMBL1320998 | 0.76 | L3MBTL1 (0.47) | HSD11B1GPR3 | |
| SCHEMBL9696764 | 0.76 | PDE2A (0.44) | PDE2APDE10ASTK10SLKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741136-B1 | Optically active dihydropyran derivative, and liquid crystal composition, liquid crystal device, and racemic mixture comprising the derivative | KASHIMA OIL (JP) | 1999-09-08 | — | — | EP | disclosed |