Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732007 | 0.84 | AR (0.31) | — | |
| SCHEMBL2432403 | 0.83 | GPR3 (0.41) | — | |
| SCHEMBL14732006 | 0.81 | PTPN5 (0.36) | — | |
| SCHEMBL14732012 | 0.79 | ALDH1A1 (0.38) | NPC1CYP1A2 | |
| SCHEMBL432357 | 0.73 | GABRP (0.41) | NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL434431 | 0.72 | L3MBTL1 (0.38) | NPC1HPGDRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL2049535 | 0.71 | HSD11B1 (0.35) | — | |
| SCHEMBL14732027 | 0.70 | CYP2A6 (0.37) | NPC1HPGDRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL7687772 | 0.70 | GPR3 (0.45) | NPC1 | |
| SCHEMBL3220922 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |