Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369024 | 0.88 | KCNH2 (0.43) | FFAR1HTTMAPK1NOS1NOS2 | |
| SCHEMBL14732901 | 0.88 | CCR1 (0.50) | CCR1CCR8TGFBR1FFAR1NOS1 | |
| SCHEMBL10369013 | 0.85 | FFAR1 (0.40) | FFAR1HTTMAPK1NOS1NOS2 | |
| SCHEMBL14733152 | 0.84 | NOS2 (0.44) | CCR1CCR8FFAR1NOS1NOS2 | |
| SCHEMBL14733158 | 0.84 | CCR1 (0.40) | CCR1CCR8TGFBR1FFAR1GAA | |
| SCHEMBL14733145 | 0.82 | IRAK4 (0.36) | CCR1CCR8TGFBR1FFAR1GAA | |
| SCHEMBL14733135 | 0.82 | LMNA (0.44) | CCR1CCR8TGFBR1FFAR1HTT | |
| SCHEMBL14733132 | 0.82 | CCR1 (0.43) | CCR1CCR8TGFBR1FFAR1NOS1 | |
| SCHEMBL14733146 | 0.81 | CCR1 (0.42) | CCR1CCR8TGFBR1FFAR1NOS1 | |
| SCHEMBL14732969 | 0.80 | CCR1 (0.64) | CCR1CCR8TGFBR1NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |