Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.44 |
| ▸ | NOS1 | P29475 | 7/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732990 | 0.86 | NOS2 (0.49) | NOS2NOS1NOS3FFAR1IDH1 | |
| SCHEMBL14733147 | 0.84 | CCR1 (0.41) | NOS2NOS1FFAR1CCR1CCR8 | |
| SCHEMBL14733145 | 0.81 | IRAK4 (0.36) | FFAR1CCR1CCR8 | |
| SCHEMBL14733061 | 0.80 | NOS2 (0.53) | NOS2NOS1BACE1NOS3CCR1 | |
| SCHEMBL14733029 | 0.80 | NOS2 (0.44) | NOS2NOS1BACE1NOS3IDH1 | |
| SCHEMBL14732989 | 0.78 | NOS2 (0.36) | NOS2NOS1BACE1NOS3IDH1 | |
| SCHEMBL14733158 | 0.76 | CCR1 (0.40) | FFAR1CCR1CCR8 | |
| SCHEMBL10369024 | 0.75 | KCNH2 (0.43) | NOS2NOS1FFAR1 | |
| SCHEMBL14732901 | 0.74 | CCR1 (0.50) | NOS2NOS1NOS3FFAR1IDH1 | |
| SCHEMBL14733154 | 0.73 | CCR1 (0.48) | FFAR1IDH1CCR1CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |