Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303087 | 0.85 | ALDH1A1 (0.37) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL13530029 | 0.85 | ALDH1A1 (0.37) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL13530336 | 0.78 | PLA2G7 (0.34) | ALDH1A1KDM4EHSD17B10MAPK1GLA | |
| SCHEMBL13529288 | 0.77 | ALDH1A1 (0.43) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2031950 | 0.76 | KDM4E (0.33) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL12585920 | 0.76 | KDM4E (0.33) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2031951 | 0.76 | KDM4E (0.33) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL13530848 | 0.74 | ALDH1A1 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL13529624 | 0.73 | CYP1A2 (0.39) | ALDH1A1KDM4ELMNAHSD17B10MAPK1 | |
| SCHEMBL3173555 | 0.73 | RAB9A (0.38) | ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562165-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |