Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729246 | 0.90 | HTR6 (0.36) | HTR6BAZ2BSIGMAR1MAPK8PTGDR2 | |
| SCHEMBL14729240 | 0.87 | HTR6 (0.38) | HTR6SIGMAR1 | |
| SCHEMBL14729252 | 0.87 | BAZ2B (0.39) | HTR6BAZ2BMAPK8CNR2 | |
| SCHEMBL13834455 | 0.87 | HTR6 (0.43) | HTR6BAZ2BSIGMAR1PTGDR2 | |
| SCHEMBL14729250 | 0.86 | KRAS (0.37) | HTR6BAZ2BSIGMAR1MAPK8CNR2 | |
| SCHEMBL14729243 | 0.84 | HTR6 (0.36) | HTR6BAZ2BSIGMAR1MAPK8PTGDR2 | |
| SCHEMBL14733461 | 0.84 | HTR6 (0.36) | HTR6BAZ2BSIGMAR1MAPK8PTGDR2 | |
| SCHEMBL14729245 | 0.84 | HTR6 (0.37) | HTR6SIGMAR1 | |
| SCHEMBL14729242 | 0.83 | HTR6 (0.38) | HTR6SIGMAR1 | |
| SCHEMBL13834550 | 0.82 | HTR6 (0.40) | HTR6SIGMAR1PTGDR2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053367-A1 | COMPOUNDS AND METHODS OF TREATING DIABETES | MEDIVATION TECHNOLOGIES, INC. | 2013-02-28 | — | — | US | disclosed |
| US-20130053367-A1 | COMPOUNDS AND METHODS OF TREATING DIABETES | MEDIVATION TECHNOLOGIES, INC. | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053367-A1 | COMPOUNDS AND METHODS OF TREATING DIABETES | ADRB2, ADRA2B, ADRA2C | HTR6 85/4885BAZ2B 664/4885SIGMAR1 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.