SCHEMBL14733797

SCHEMBL14733797

c1ccc(-c2cccc3c2sc2c(-c4ccccc4-c4cccc(-n5c6ccccc6c6ccccc65)c4)cccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
LIMK1 P53667 1/20 0.39
ALOX5 P09917 1/20 0.38
MAPK14 Q16539 1/20 0.34
KMT2A Q03164 3/20 0.33
GRM5 P41594 1/20 0.33
IL1R1 P14778 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDE10A Q9Y233 1/20 0.32
ASH1L Q9NR48 3/20 0.32
TDO2 P48775 1/20 0.31
FOLH1 Q04609 1/20 0.30
GAA P10253 1/20 0.30
F9 P00740 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24677155 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL17038418 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL24295147 0.89 L3MBTL1 (0.57) L3MBTL1KDM4EATMMAPK14KMT2A
SCHEMBL15988943 0.88 L3MBTL1 (0.45) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL23072323 0.88 ATM (0.41) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL17038426 0.88 L3MBTL1 (0.41) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL10029283 0.88 ALOX5 (0.49) L3MBTL1KDM4EATMALOX5MAPT
SCHEMBL13829535 0.88 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL24677420 0.87 L3MBTL1 (0.42) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL10165719 0.86 L3MBTL1 (0.49) L3MBTL1KDM4EATMLIMK1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed