SCHEMBL24677155

SCHEMBL24677155

c1ccc(-c2cccc3c2sc2c(-c4cccc(-n5c6ccccc6c6cc(-n7c8ccccc8c8ccccc87)ccc65)c4)cccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
LIMK1 P53667 1/20 0.39
ALOX5 P09917 1/20 0.37
RAC2 P15153 1/20 0.36
RAC3 P60763 1/20 0.36
CDC42 P60953 1/20 0.36
RAC1 P63000 1/20 0.36
MAPK14 Q16539 1/20 0.33
KMT2A Q03164 2/20 0.33
IL1R1 P14778 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDE10A Q9Y233 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24677179 0.93 L3MBTL1 (0.45) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL15988943 0.92 L3MBTL1 (0.45) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL17038418 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL13829535 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL24677154 0.91 L3MBTL1 (0.41) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL780563 0.91 ALOX5 (0.38) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL14733797 0.91 L3MBTL1 (0.45) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL10165693 0.91 L3MBTL1 (0.49) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL780797 0.90 KDM4E (0.40) L3MBTL1KDM4EATMLIMK1ALOX5
SCHEMBL780700 0.90 KDM4E (0.40) L3MBTL1KDM4EATMLIMK1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-11485706-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485706-B2 Organic electroluminescent materials and devices SOD1, L1CAM, EPCAM L3MBTL1 1135/4885KDM4E 3594/4885ATM 1277/4885
US-20230159550-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 L3MBTL1 888/4885KDM4E 2090/4885ATM 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.