Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734402 | 0.82 | RAD52 (0.40) | RAD52ADORA2AADORA1HTTSMN1; SMN2 | |
| SCHEMBL14734375 | 0.80 | MAPT (0.47) | PTPN1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL15228695 | 0.74 | PTPN1 (0.43) | RAD52PTPN1ALDH1A1LMNAMAPT | |
| SCHEMBL14734397 | 0.74 | MAPT (0.44) | RAD52ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL2021969 | 0.73 | CYP1A2 (0.46) | RAD52ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL2131272 | 0.72 | ACHE (0.41) | RAD52DHODHALDH1A1LMNAMAPT | |
| SCHEMBL30118358 | 0.71 | PIM1 (0.42) | RAD52ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL15228873 | 0.69 | PTPN1 (0.43) | RAD52PTPN1ALDH1A1LMNAMAPT | |
| SCHEMBL14734341 | 0.68 | PIM1 (0.40) | RAD52ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL21857858 | 0.68 | PARP1 (0.40) | RAD52ALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027794-A1 | NOVEL COMPOUND AND USE THEREOF AS PDE10 INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2013-02-28 | — | — | WO | disclosed |