Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734356 | 0.82 | RAD52 (0.40) | RAD52ADORA2AADORA1HTTSMN1; SMN2 | |
| SCHEMBL14734397 | 0.79 | MAPT (0.44) | RAD52GAAPARP1NPC1RAB9A | |
| SCHEMBL4833903 | 0.77 | MAPT (0.54) | TP53HSD17B10GAAHTTNPC1 | |
| SCHEMBL2131272 | 0.76 | ACHE (0.41) | RAD52GAAPARP1NPC1RAB9A | |
| SCHEMBL30118358 | 0.75 | PIM1 (0.42) | RAD52GAAPARP1NPC1RAB9A | |
| SCHEMBL2021969 | 0.75 | CYP1A2 (0.46) | RAD52HSD17B10GAAHTTNPC1 | |
| SCHEMBL14734341 | 0.73 | PIM1 (0.40) | RAD52GAAPARP1NPC1RAB9A | |
| SCHEMBL15228445 | 0.71 | ALDH1A1 (0.44) | RAD52TP53HSD17B10GAAPARP1 | |
| SCHEMBL18306132 | 0.70 | ALDH1A1 (0.46) | TP53HSD17B10HTTRAB9ASMN1; SMN2 | |
| SCHEMBL1695174 | 0.70 | SMN1; SMN2 (0.50) | TP53HSD17B10HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027794-A1 | NOVEL COMPOUND AND USE THEREOF AS PDE10 INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2013-02-28 | — | — | WO | disclosed |