Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734629 | 0.91 | HTT (0.53) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14722881 | 0.88 | TDP1 (0.48) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14722879 | 0.88 | TDP1 (0.48) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734651 | 0.87 | PRSS1 (0.40) | HTTPOLBAPEX1TDP1RAB9A | |
| SCHEMBL14734643 | 0.83 | ESR1 (0.38) | HTTPOLBKCNH2RAB9ANPC1 | |
| SCHEMBL14734663 | 0.82 | HTT (0.58) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734665 | 0.78 | RAB9A (0.44) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL14734620 | 0.78 | HTT (0.58) | HTTPOLBAPEX1TDP1GAA | |
| SCHEMBL15861984 | 0.78 | PTPN7 (0.41) | HTTPOLBAPEX1TDP1MEN1 | |
| SCHEMBL15861983 | 0.78 | PTPN7 (0.41) | HTTPOLBAPEX1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |