Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734843 | 0.88 | NPC1 (0.40) | SMYD3NPC1RAB9AJAK2JAK1 | |
| SCHEMBL591754 | 0.84 | NPC1 (0.47) | SMYD3NPC1RAB9AJAK2JAK1 | |
| SCHEMBL3206636 | 0.83 | ALOX5 (0.46) | NPC1RAB9AKDM4ELMNAMAPK1 | |
| SCHEMBL2695326 | 0.81 | EGLN1 (0.42) | SMYD3NPC1RAB9AJAK2JAK1 | |
| SCHEMBL589973 | 0.77 | NPC1 (0.46) | SMYD3NPC1RAB9AJAK2JAK1 | |
| SCHEMBL17238837 | 0.75 | MAOA (0.34) | KDM4ELMNA | |
| SCHEMBL634151 | 0.75 | KDM4E (0.42) | NPC1KDM4EMAPK1 | |
| SCHEMBL2693742 | 0.74 | IRAK4 (0.40) | SMYD3NPC1RAB9AJAK2JAK1 | |
| SCHEMBL2694674 | 0.74 | NPC1 (0.54) | SMYD3NPC1RAB9AJAK2JAK1 | |
| SCHEMBL14735049 | 0.74 | PIM1 (0.47) | NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564706-A1 | Anthranilamide insecticides | E. I. du Pont de Nemours and Company (US) | 2013-03-06 | — | — | EP | claimed |
| CN-101061103-B | Anthranilamide insecticides | DU PONT | 2012-12-12 | — | — | CN | claimed |