Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14734834 | 0.83 | SMYD3 (0.41) | LMNAKDM4ENPC1RAB9AMAPK1 | |
| SCHEMBL17238837 | 0.82 | MAOA (0.34) | ALOX5MAOAMAOBALDH1A1HTT | |
| SCHEMBL634151 | 0.81 | KDM4E (0.42) | ALDH1A1HTTKDM4EPKMPOLB | |
| SCHEMBL2489605 | 0.81 | ALOX5 (0.46) | ALOX5ALDH1A1HTTCHRM4KDM4E | |
| SCHEMBL759268 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EPKMPOLBHPGD | |
| SCHEMBL30784123 | 0.77 | ALOX5 (0.46) | ALOX5MAOAMAOBALDH1A1HTT | |
| SCHEMBL29101565 | 0.77 | KDM4E (0.39) | ALDH1A1LMNAKDM4EPKMHPGD | |
| SCHEMBL31431699 | 0.77 | ALOX5 (0.43) | ALOX5MAOAMAOBALDH1A1CHRM4 | |
| SCHEMBL23243625 | 0.77 | ALDH1A1 (0.57) | ALOX5MAOAMAOBALDH1A1HTT | |
| SCHEMBL26905965 | 0.77 | HTT (0.54) | ALOX5MAOAMAOBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467988-B1 | Quinazoline(di)ones for invertebrate pest control | DU PONT (US) | 2013-07-17 | — | — | EP | disclosed |
| US-7683201-B2 | Quinazoline(di)ones for invertebrate pest control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-23 | — | — | US | disclosed |
| CN-101659655-A | Pyrazole amide derivative and application thereof | UNIV NANKAI | 2010-03-03 | — | — | CN | disclosed |
| CN-101134755-A | Quinazoline(di) ones for invertebrate pest control | DU PONT (US) | 2008-03-05 | — | — | CN | disclosed |
| CN-100349890-C | Quinazolinone (di) ones for controlling invertebrate pests | DU PONT (US) | 2007-11-21 | — | — | CN | disclosed |
| US-7241767-B2 | Quinazoline(di)ones for invertebrate pest control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060194961-A1 | Quinazoline(di)ones for invertebrate pest control | FMC CORPORATION | 2006-08-31 | — | — | US | disclosed |
| US-20050124600-A1 | Quinazoline(di)ones for invertebrate pest control | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-06-09 | — | — | US | disclosed |
| CN-1620450-A | Quinazolinone (di) ones for controlling invertebrate pests | DU PONT (US) | 2005-05-25 | — | — | CN | disclosed |
| EP-1467988-A1 | QUINAZOLINE(DI)ONES FOR INVERTEBRATE PEST CONTROL | E. I. du Pont de Nemours and Company (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003062226-A1 | QUINAZOLINE(DI) ONES FOR INVERTEBRATE PEST CONTROL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124600-A1 | Quinazoline(di)ones for invertebrate pest control | DDT, BRS3, F12 | ALOX5 1245/4885MAOA 837/4885MAOB 351/4885 |
| US-20060194961-A1 | Quinazoline(di)ones for invertebrate pest control | F12, DDT, SBK3 | ALOX5 1275/4885MAOA 1294/4885MAOB 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.