Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2535721 | 0.90 | LMNA (0.33) | MEN1MAPTKMT2A | |
| SCHEMBL12220256 | 0.88 | LMNA (0.33) | MEN1MAPTKMT2A | |
| Iodide SCHEMBL2530877 | 0.84 | QDPR (0.34) | MEN1KMT2A | |
| Iodide SCHEMBL14738436 | 0.82 | F2 (0.34) | NOTUMMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12220215 | 0.82 | QDPR (0.35) | MEN1KMT2A | |
| Iodide SCHEMBL2040900 | 0.81 | HDAC8 (0.41) | NOTUMALDH1A1MGLLTUBB4ATUBB | |
| Iodide SCHEMBL3820106 | 0.80 | LMNA (0.40) | MEN1MAPTKMT2A | |
| Iodide SCHEMBL15993275 | 0.79 | MGLL (0.39) | MEN1ALDH1A1MAPTKMT2AMGLL | |
| Iodide SCHEMBL15993620 | 0.78 | CYP1A2 (0.47) | MEN1ALDH1A1MAPTPKMKMT2A | |
| SCHEMBL666881 | 0.78 | LMNA (0.41) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170054094-A1 | Transition Metal Carbene Complexes and the Electroluminescent Application Thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-02-23 | — | — | US | disclosed |
| US-9518217-B2 | Transition metal carbene complexes and the electroluminescent application thereof | E INK HOLDINGS INC. (TW) | 2016-12-13 | — | — | US | disclosed |
| CN-102977150-A | Transition metal complex structure containing carbene ligand and application thereof in luminescent material | CHENG CHIEN-HONG | 2013-03-20 | — | — | CN | disclosed |
| US-20130056716-A1 | TRANSITION METAL CARBENE COMPLEXES AND THE ELECTROLUMINESCENT APPLICATION THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130056716-A1 | TRANSITION METAL CARBENE COMPLEXES AND THE ELECTROLUMINESCENT APPLICATION THEREOF | L1CAM, MB, CYBA | ACHE 558/4885NOTUM 4551/4885MEN1 2166/4885 |
| US-20170054094-A1 | Transition Metal Carbene Complexes and the Electroluminescent Application Thereof | MB, CYBA, L1CAM | ACHE 732/4885NOTUM 4490/4885MEN1 1600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.