Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2535721 | 0.90 | LMNA (0.33) | LMNAHTTATM | |
| SCHEMBL12220256 | 0.88 | LMNA (0.33) | LMNAHTTATM | |
| Iodide SCHEMBL2530877 | 0.84 | QDPR (0.34) | APOBEC3GLMNAALOX15 | |
| Iodide SCHEMBL14738436 | 0.82 | F2 (0.34) | NOTUMELANEPOLBMGLLTDP1 | |
| SCHEMBL12220215 | 0.82 | QDPR (0.35) | APOBEC3GLMNAALOX15 | |
| Iodide SCHEMBL14739461 | 0.81 | NOTUM (0.32) | NOTUMMGLLTUBB4ATUBBTUBA3C | |
| Iodide SCHEMBL3820106 | 0.80 | LMNA (0.40) | POLBAPOBEC3GLMNAATM | |
| Iodide SCHEMBL15993275 | 0.79 | MGLL (0.39) | POLBMGLLAPOBEC3GTDP1LMNA | |
| Iodide SCHEMBL15993620 | 0.78 | CYP1A2 (0.47) | POLBMGLLTDP1LMNATUBB4A | |
| SCHEMBL666881 | 0.78 | LMNA (0.41) | APOBEC3GLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877937-B2 | Process for preparing transition metal-carbene complexes | BASF SE (DE) | 2014-11-04 | — | — | US | disclosed |
| US-20130178621-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | BASF SE (DE) | 2013-07-11 | — | — | US | disclosed |
| EP-2338593-B1 | Process for the preparation of transition metal carbene complexes | BASF SE (DE) | 2013-06-19 | — | — | EP | disclosed |
| US-8410280-B2 | Process for preparing transition metal-carbene complexes | BASF SE (DE) | 2013-04-02 | — | — | US | disclosed |
| EP-2338593-A1 | Process for the preparation of transition metal carbene complexes | BASF SE (DE) | 2011-06-29 | — | — | EP | disclosed |
| EP-1819717-B1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF SE (DE) | 2009-07-08 | — | — | EP | disclosed |
| US-20090018330-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | BASF SE (DE) | 2009-01-15 | — | — | US | disclosed |
| EP-1993728-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | BASF SE (DE) | 2008-11-26 | — | — | EP | disclosed |
| EP-1819717-A2 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2007088093-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | BASF SE (DE) | 2007-08-09 | — | — | WO | disclosed |
| WO-2006056418-A2 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018330-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | AP1M1, C1S, GPS1 | HDAC8 4712/4885NOTUM 4568/4885ELANE 4115/4885 |
| US-20130178621-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | AP1M1, C1S, GPS1 | HDAC8 4712/4885NOTUM 4568/4885ELANE 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.