SCHEMBL1473993

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1474515	0.83	ALDH1A1 (0.58)	HDAC1ALDH1A1LMNAMAPK1ALOX15
	SCHEMBL161364	0.79	ALDH1A1 (0.50)	ALDH1A1LMNAHSD17B10TDP1RAB9A
	SCHEMBL4874815	0.78	SMN1; SMN2 (0.43)	ALDH1A1LMNARAB9ANPC1MAPT
	SCHEMBL13685216	0.72	NR1H4 (0.50)	HDAC1ALDH1A1LMNARAB9ANPC1
	SCHEMBL7785831	0.72	HDAC1 (0.45)	HDAC1ALDH1A1LMNAMAPK1ALOX15
	SCHEMBL25161985	0.72	CYP1A2 (0.45)	HDAC1ALDH1A1LMNAMAPK1ALOX15
	SCHEMBL9997587	0.72	CYP1A2 (0.45)	ALDH1A1LMNAMAPK1ALOX15APEX1
	SCHEMBL9997585	0.72	CYP1A2 (0.45)	ALDH1A1LMNAMAPK1ALOX15APEX1
	SCHEMBL2092731	0.72	ALDH1A1 (0.60)	ALDH1A1LMNARAB9ANPC1MAPT
	SCHEMBL3084919	0.71	MAPT (0.58)	HDAC1ALDH1A1RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.