Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9998126 | 0.92 | CYP1A2 (0.41) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9998124 | 0.92 | CYP1A2 (0.41) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9998449 | 0.90 | CYP1A2 (0.40) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9998448 | 0.90 | CYP1A2 (0.40) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9997585 | 0.87 | CYP1A2 (0.45) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9997587 | 0.87 | CYP1A2 (0.45) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9997754 | 0.86 | LMNA (0.45) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9997752 | 0.86 | LMNA (0.45) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9998161 | 0.83 | CYP1A2 (0.41) | CYP1A2SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL13410929 | 0.79 | GSK3B (0.47) | CYP1A2SMN1; SMN2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230121556-A1 | COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230121556-A1 | COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE | LTB4R, LTC4S, LTA4H | CYP1A2 2001/4885SMN1; SMN2 3664/4885LMNA 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.