Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14375353 | 0.84 | ELANE (0.40) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL8846909 | 0.75 | TYR (0.42) | KDM4EHPGDHSD17B10TDP1ALDH1A1 | |
| SCHEMBL6278245 | 0.75 | ALDH1A1 (0.49) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL15232973 | 0.74 | KDM4E (0.36) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL27432511 | 0.74 | AKR1C3 (0.46) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL9242437 | 0.73 | KDM4E (0.47) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL15104783 | 0.73 | PTGS2 (0.38) | KDM4EHPGDHSD17B10TDP1ALDH1A1 | |
| SCHEMBL9542306 | 0.72 | KDM4E (0.41) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL28054238 | 0.72 | MAPT (0.40) | KDM4EMAPTCYP3A4ALOX15HPGD | |
| SCHEMBL667361 | 0.72 | KDM4E (0.40) | KDM4EMAPTHPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059952-A1 | PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS | BASF SE (DE) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059952-A1 | PHOSPHO-SUBSTITUTED ALKOXYAMINE COMPOUNDS | PFAS, PHOSPHO1, PIK3CA | KDM4E 1595/4885MAPT 676/4885CYP3A4 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.