Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28550151 | 0.81 | PAM (0.50) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9586306 | 0.78 | ELANE (0.45) | PARP1KMT2APKMSMN1; SMN2ALDH1A1 | |
| Thiobenzoic Acid SCHEMBL162937 | 0.76 | PAM (0.46) | MEN1KMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| Thiobenzoic Acid SCHEMBL10793587 | 0.73 | PAM (0.43) | MEN1KMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| Thiobenzoic Acid SCHEMBL4832164 | 0.72 | CA2 (0.42) | ERCC5FEN1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9446699 | 0.71 | PAM (0.67) | MEN1KMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11852856 | 0.71 | MEN1 (0.49) | ERCC5FEN1PARP1MEN1KMT2A | |
| SCHEMBL29360692 | 0.70 | PARP1 (0.65) | ERCC5FEN1PARP1RAB9AL3MBTL1 | |
| Benzene SCHEMBL28107074 | 0.70 | PARP1 (0.65) | ERCC5FEN1PARP1RAB9AL3MBTL1 | |
| SCHEMBL38766 | 0.70 | PARP1 (0.65) | ERCC5FEN1PARP1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598441-B2 | Therapeutic compounds and methods | WAYNE STATE UNIVERSITY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20140221412-A1 | THERAPEUTIC COMPOUNDS AND METHODS | WAYNE STATE UNIVERSITY (US) | 2014-08-07 | — | — | US | disclosed |
| EP-2750508-A1 | THERAPEUTIC COMPOUNDS AND METHODS | Wayne State University (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033392-A1 | THERAPEUTIC COMPOUNDS AND METHODS | WAYNE STATE UNIVERSITY (US) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221412-A1 | THERAPEUTIC COMPOUNDS AND METHODS | XPOT, FANCI, XPO5 | ERCC5 495/4885FEN1 1562/4885PARP1 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.