Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1544957 | 0.80 | DGAT1 (0.53) | ELANETRPV1SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL9587166 | 0.80 | MEN1 (0.46) | SMN1; SMN2PARP1CTSLMAPTLMNA | |
| SCHEMBL197307 | 0.79 | TRPV1 (0.61) | ELANETRPV1SMN1; SMN2PARP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1544955 | 0.79 | DGAT1 (0.51) | ELANETRPV1SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL29443099 | 0.79 | TRPV1 (0.61) | ELANETRPV1SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL14537322 | 0.79 | ELANE (0.45) | ELANETRPV1SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL14740677 | 0.78 | ERCC5 (0.47) | SMN1; SMN2PKMPARP1ALDH1A1TDP1 | |
| SCHEMBL7527945 | 0.77 | CES2 (0.53) | ELANESMN1; SMN2PARP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27624411 | 0.77 | TRPV1 (0.59) | ELANETRPV1SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL9585635 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |