Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402758 | 0.82 | CHRNB2 (0.57) | CHRNB2CHRNB4CHRNA4GPR84PPARG | |
| SCHEMBL247201 | 0.78 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA4CHRNA3 | |
| Acetic Acid SCHEMBL29701279 | 0.76 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA4GPR84CHRNA3 | |
| Adipic Acid SCHEMBL536407 | 0.75 | AKR1B1 (0.74) | AKR1B1GPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL28541199 | 0.75 | AKR1B1 (0.74) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL14218282 | 0.75 | GABRP (0.45) | CHRNB2CHRNB4CHRNA4AKR1B1GPR84 | |
| SCHEMBL27569559 | 0.74 | CHRNB2 (0.67) | CHRNB2CHRNB4CHRNA4ALOX15KMT2A | |
| Acetic Acid SCHEMBL31579080 | 0.73 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA4GPR84PPARD | |
| Butyric Acid SCHEMBL8168104 | 0.73 | FFAR3 (0.52) | CHRNB2CHRNB4CHRNA4AKR1B1GPR84 | |
| Oxalic Acid SCHEMBL11335719 | 0.73 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA4GPR84PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033046-A2 | FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | VIGH GYULA (US) | 2013-03-07 | — | — | WO | disclosed |