SCHEMBL14743162

SCHEMBL14743162

CCc1cc([C]=O)ccc1-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.37
KMT2A Q03164 1/20 0.36
EGLN2 Q96KS0 1/20 0.35
MMP2 P08253 2/20 0.35
MMP3 P08254 2/20 0.35
PTGS1 P23219 1/20 0.35
ESR2 Q92731 1/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GALR3 O60755 1/20 0.34
GAA P10253 1/20 0.34
HPGD P15428 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
FBP1 P09467 1/20 0.34
BACE1 P56817 2/20 0.33
MAPK1 P28482 2/20 0.33
ALOX5 P09917 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4664566 0.84 EGLN2 (0.49) KMT2AEGLN2ALDH1A1KDM4EGALR3
SCHEMBL9618333 0.77 SMN1; SMN2 (0.47) DPP4KMT2AMMP2MMP3PTGS1
SCHEMBL371299 0.77 FFAR1 (0.41) L3MBTL1
SCHEMBL30112562 0.76 BACE1 (0.44) DPP4KMT2APTGS1ESR2BACE1
SCHEMBL30500513 0.76 NPC1 (0.53) DPP4KMT2AALDH1A1MAPK1NPC1
SCHEMBL4629941 0.76 DPP4 (0.41) DPP4KMT2AMMP2MMP3PTGS1
SCHEMBL18569389 0.76 PTGDR2 (0.46) DPP4KMT2AMMP2MMP3PTGS1
SCHEMBL3026732 0.74 GABRA1 (0.34) MAPT
SCHEMBL2322002 0.74 LMNA (0.46) KMT2APTGS1HPGDBACE1ALOX5
SCHEMBL2324271 0.74 KDM4E (0.40) KMT2AESR2ALDH1A1KDM4EGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013032016-A1 CELLULOSE ACYLATE FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-03-07 WO disclosed