Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856481 | 0.81 | PTGDR2 (0.49) | KDM4EALDH1A1L3MBTL1GAAGALR3 | |
| SCHEMBL29788076 | 0.81 | PTGDR2 (0.49) | KDM4EALDH1A1L3MBTL1GAAGALR3 | |
| SCHEMBL3966108 | 0.76 | CA12 (0.52) | BACE1SMN1; SMN2MCL1 | |
| SCHEMBL14743162 | 0.74 | DPP4 (0.37) | KDM4EESR2ALDH1A1L3MBTL1GAA | |
| SCHEMBL5582180 | 0.74 | KDM4E (0.44) | KDM4EL3MBTL1GAACYP1A2FFAR1 | |
| SCHEMBL2322002 | 0.73 | LMNA (0.46) | HPGDBACE1CYP1A2PDE4APDE3B | |
| SCHEMBL29535942 | 0.73 | HDAC7 (0.50) | KDM4EESR2CYP2A6CYP2B6ALDH1A1 | |
| SCHEMBL7930011 | 0.73 | L3MBTL1 (0.47) | KDM4EESR2CYP2A6CYP2B6ALDH1A1 | |
| SCHEMBL277849 | 0.73 | HDAC7 (0.50) | KDM4EESR2CYP2A6CYP2B6ALDH1A1 | |
| SCHEMBL98096 | 0.72 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |