Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744302 | 0.86 | ACLY (0.46) | TPMTMEN1KMT2ACYP1A2BLM | |
| SCHEMBL14743646 | 0.86 | TSHR (0.43) | MEN1KMT2ACYP1A2LMNANPC1 | |
| SCHEMBL14743558 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2ATSHRHPGD | |
| SCHEMBL14743334 | 0.83 | HTT (0.37) | MEN1KMT2AMAPK1RXRARXRB | |
| SCHEMBL14743655 | 0.82 | TSHR (0.42) | MEN1KMT2AMAPK1NPC1TSHR | |
| SCHEMBL14743619 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2ARXRAMRGPRX4SLC6A4 | |
| SCHEMBL14743568 | 0.80 | MRGPRX4 (0.36) | MEN1KMT2ACYP1A2BLMLMNA | |
| SCHEMBL14743723 | 0.77 | KDM4E (0.47) | KMT2A | |
| SCHEMBL14743090 | 0.77 | MEN1 (0.43) | MEN1KMT2AMAPK1RAB9AMRGPRX4 | |
| SCHEMBL14743302 | 0.75 | NPC1 (0.47) | MEN1KMT2ANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |