Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743723 | 0.90 | KDM4E (0.47) | ACLYGPBAR1KMT2A | |
| SCHEMBL14743979 | 0.88 | TSHR (0.42) | ACLYNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14743805 | 0.87 | GPBAR1 (0.43) | NPC1RAB9AALDH1A1HTTL3MBTL1 | |
| SCHEMBL14743702 | 0.86 | TPMT (0.40) | NPC1RAB9AHPGDTPMTLMNA | |
| SCHEMBL14743489 | 0.86 | GAA (0.41) | ACLYNPC1RAB9AL3MBTL1GPBAR1 | |
| SCHEMBL14743558 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HPGDHTTMEN1 | |
| SCHEMBL14743459 | 0.84 | ACLY (0.36) | ACLYNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14743833 | 0.83 | MAPT (0.38) | ACLYNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14743407 | 0.83 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14743619 | 0.82 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1HPGDL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |