Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898212 | 0.83 | RORC (0.50) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14746593 | 0.81 | HSD17B10 (0.45) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744240 | 0.79 | HSPB1 (0.47) | — | |
| SCHEMBL14746574 | 0.78 | HSD17B10 (0.45) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744191 | 0.78 | RORC (0.44) | RORCCYP2C9CYP2C19MAP2 | |
| SCHEMBL16014414 | 0.75 | ALDH1A1 (0.48) | RORC | |
| SCHEMBL14743963 | 0.74 | PDE7A (0.48) | RORC | |
| SCHEMBL14746769 | 0.74 | RORC (0.46) | RORCCYP2C9CYP2C19 | |
| SCHEMBL7686888 | 0.72 | HSD17B10 (0.55) | CYP2C9CYP2C19 | |
| SCHEMBL14744202 | 0.71 | RORC (0.50) | RORCCYP2C9CYP2C19MAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |