Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746593 | 0.85 | HSD17B10 (0.45) | HSPB1PTPRCS100A4BCHEACHE | |
| SCHEMBL14746841 | 0.84 | PTGS2 (0.50) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14746574 | 0.82 | HSD17B10 (0.45) | HSPB1PTPRCS100A4BCHEACHE | |
| SCHEMBL14744323 | 0.82 | PTPRC (0.40) | HSPB1ALOX5APFEN1PTPRCS100A4 | |
| SCHEMBL8643566 | 0.81 | HSPB1 (0.51) | HSPB1AKR1C3AKR1C2MAPTALDH1A1 | |
| SCHEMBL14744328 | 0.80 | CYP19A1 (0.52) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14744525 | 0.80 | PTPRC (0.39) | HSPB1PTPRCS100A4BCHEACHE | |
| SCHEMBL14744101 | 0.79 | RORC (0.45) | — | |
| SCHEMBL14744562 | 0.79 | AKR1C3 (0.44) | AKR1C3AKR1C2MAPTALDH1A1NPSR1 | |
| SCHEMBL14744381 | 0.79 | GAA (0.49) | MAPTCYP1A2ALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |