Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895959 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTTRPA1LMNA | |
| SCHEMBL13882617 | 0.83 | CA1 (0.47) | CA1CA2CA9CA5ACA5B | |
| SCHEMBL23854165 | 0.83 | CA1 (0.47) | CA1CA2CA9CA5ACA5B | |
| SCHEMBL13475881 | 0.79 | CA1 (0.48) | ALDH1A1KDM4ECA1CA2CA9 | |
| SCHEMBL17818208 | 0.79 | STAT3 (0.43) | ALDH1A1MAPTLMNAALOX5CA1 | |
| SCHEMBL30002551 | 0.78 | CA1 (0.52) | ALDH1A1KDM4ECA1CA2CA9 | |
| SCHEMBL18845153 | 0.76 | CA1 (0.41) | CA1CA2CA9CA5ACA5B | |
| SCHEMBL13668357 | 0.76 | TP53 (0.42) | ALDH1A1KDM4ELMNACA1CA2 | |
| SCHEMBL27742228 | 0.76 | CA1 (0.41) | ALOX5CA1CA2CA9CA5A | |
| SCHEMBL27738663 | 0.76 | CA1 (0.41) | ALOX5CA1CA2CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751124-B1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | claimed |
| US-9242925-B2 | Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-01-26 | — | — | US | claimed |
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-12-11 | — | — | US | claimed |
| EP-2751124-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | Centre National de la Recherche Scientifique (CNRS) (FR) | 2014-07-09 | — | — | EP | claimed |
| WO-2013030193-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-07 | — | — | WO | claimed |
| CN-107253968-B | Universal and stereospecific synthesis of gamma, delta-unsaturated amino acids by Wittig reaction | 国家科学研究中心 | 2020-03-13 | — | — | CN | disclosed |
| WO-2020021735-A1 | RESIN-COATED METALLIC PIGMENT | DIC株式会社 | 2020-01-30 | — | — | WO | disclosed |
| EP-2751124-B1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |
| EP-2751124-B1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |
| US-9242925-B2 | Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-01-26 | — | — | US | disclosed |
| US-9242925-B2 | Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-01-26 | — | — | US | disclosed |
| US-9242925-B2 | Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-01-26 | — | — | US | disclosed |
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-12-11 | — | — | US | disclosed |
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-12-11 | — | — | US | disclosed |
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-12-11 | — | — | US | disclosed |
| EP-2751124-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | Centre National de la Recherche Scientifique (CNRS) (FR) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013030193-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013030193-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | BCAT1, BCAT2, ALAD | ALDH1A1 380/4885KDM4E 3708/4885MAPT 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.