Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31588114 | 0.78 | KHK (0.41) | KHKCYP11B1CYP11B2TRPV4EGLN2 | |
| SCHEMBL2651893 | 0.78 | TRPV4 (0.39) | KHKCYP11B1CYP11B2TRPV4ESR1 | |
| SCHEMBL504980 | 0.78 | KHK (0.41) | KHKCYP11B1CYP11B2TRPV4EGLN2 | |
| SCHEMBL238421 | 0.77 | KDM1A (0.44) | ALDH1A1MAPTGAACYP3A4KDM1A | |
| SCHEMBL20095956 | 0.75 | CYP11B1 (0.37) | KHKCYP11B1CYP11B2TRPV4EGLN2 | |
| SCHEMBL14744340 | 0.75 | CYP3A4 (0.41) | KHKTRPV4KDM4EALDH1A1USP2 | |
| SCHEMBL21051816 | 0.75 | KDM4E (0.40) | EGLN2KDM4EALDH1A1USP2LMNA | |
| SCHEMBL22119927 | 0.75 | KHK (0.39) | KHKCYP11B1CYP11B2TRPV4EGLN2 | |
| SCHEMBL20095954 | 0.72 | TRPV4 (0.34) | KHKCYP11B1CYP11B2TRPV4ESR1 | |
| SCHEMBL20329648 | 0.71 | TRPV4 (0.33) | CYP11B1CYP11B2TRPV4ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133915-A1 | COMPOUNDS WHICH BIND TO PNPLA3I148M AND THEIR USE TO TREAT LIVER DISEASES | NOVARTIS AG (CH) | 2025-06-26 | — | — | WO | disclosed |
| US-20190177284-A1 | TETRAZOLYL-CONTAINING CYCLOPROPANECARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-13 | — | — | US | disclosed |
| US-20190177284-A1 | TETRAZOLYL-CONTAINING CYCLOPROPANECARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-13 | — | — | US | disclosed |
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190177284-A1 | TETRAZOLYL-CONTAINING CYCLOPROPANECARBOXAMIDES | GAP43, PSEN1, PSEN2 | KHK 4411/4885CYP11B1 846/4885CYP11B2 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.