Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071274 | 0.89 | MEN1 (0.48) | RORCMEN1KMT2A | |
| SCHEMBL14744062 | 0.82 | RORC (0.51) | RORC | |
| SCHEMBL14744293 | 0.77 | RAB9A (0.53) | RORC | |
| SCHEMBL14744156 | 0.77 | RORC (0.50) | RORC | |
| SCHEMBL16800012 | 0.75 | RORC (0.72) | RORC | |
| SCHEMBL14744474 | 0.75 | RORC (0.71) | RORCMEN1KMT2A | |
| SCHEMBL14744122 | 0.75 | RORC (0.52) | RORC | |
| SCHEMBL14744325 | 0.74 | RORC (0.68) | RORC | |
| SCHEMBL18156914 | 0.74 | RORC (0.60) | RORC | |
| SCHEMBL14744303 | 0.73 | RORC (0.53) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |