Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258566 | 0.83 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL23845573 | 0.81 | MAPT (0.60) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL6701189 | 0.79 | MEN1 (0.62) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL29977958 | 0.79 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL1256644 | 0.79 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL10516843 | 0.78 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL17645850 | 0.78 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 | |
| SCHEMBL22212570 | 0.78 | GAA (0.45) | MAPTMEN1KMT2ATDP1GAA | |
| SCHEMBL2171617 | 0.78 | GAA (0.45) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29483829 | 0.77 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2ALDH1A1CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427411-A | 5- (3- (ethylsulfonyl) pyridin-2-yl) -pyrazolo [1,5-a ] pyrimidine derivatives and related compounds as pesticides for crop protection | PI工业有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-109689630-B | Diaryl azole compound and pest control agent | 日本曹达株式会社 | 2022-06-03 | — | — | CN | disclosed |
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2019-05-23 | — | — | US | disclosed |
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2019-05-23 | — | — | US | disclosed |
| EP-3481809-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | Cadila Healthcare Limited (IN) | 2019-05-15 | — | — | EP | disclosed |
| CN-109689630-A | Diaryl azole compound and pest control agent | 日本曹达株式会社 | 2019-04-26 | — | — | CN | disclosed |
| WO-2018011746-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2018-01-18 | — | — | WO | disclosed |
| WO-2018011746-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2018-01-18 | — | — | WO | disclosed |
| CN-102216265-B | Naphthylacetic acid | HOFFMANN LA ROCHE | 2014-04-30 | — | — | CN | disclosed |
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | RORC, RORB, RORA | MAPT 265/4885SMN1; SMN2 3885/4885ALDH1A1 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.