Sugi Predict

Sugi Predict / Compounds / SCHEMBL147446

SCHEMBL147446

SCHEMBL147446

NC(=S)Nc1cccc(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 1/20 0.68
▸ KMT2A Q03164 3/20 0.63
▸ CYP1A2 P05177 1/20 0.61
▸ ALDH1A1 P00352 4/20 0.57
▸ GAA P10253 3/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ TSHR P16473 2/20 0.57
▸ MAPT P10636 1/20 0.57
▸ HTT P42858 1/20 0.57
▸ TP53 P04637 1/20 0.57
▸ TYR P14679 1/20 0.57
▸ TAS2R38 P59533 1/20 0.57
▸ HSD17B10 Q99714 1/20 0.57
▸ POLB P06746 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ NPC1 O15118 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838519 1.00 IDO1 (0.68) IDO1KMT2ACYP1A2ALDH1A1GAA
SCHEMBL4047674 0.85 KMT2A (0.76) IDO1KMT2ACYP1A2ALDH1A1GAA
SCHEMBL13246382 0.84 GAA (0.63) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL25633561 0.83 IDO1 (0.79) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL9319543 0.81 IDO1 (1.00) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL20560279 0.80 IDO1 (0.62) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL11493526 0.80 IDO1 (0.62) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL3443268 0.80 IDO1 (0.58) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL167713 0.80 MEN1 (0.67) IDO1KMT2AALDH1A1GAAMEN1
SCHEMBL1748177 0.79 ALDH1A1 (0.48) IDO1KMT2ACYP1A2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118480151-A Optical-grade methyl methacrylate copolymer, and preparation method and application thereof 中国石油化工股份有限公司 2024-08-13 — — CN claimed
CN-112582673-A Lithium ion battery electrolyte and lithium ion battery 比亚迪股份有限公司 2021-03-30 — — CN claimed
CN-103373969-A Phenyl imidazole ring-substituted amide compounds as well as preparation method and application for same SHANGHAI INST ORGANIC CHEM 2013-10-30 — — CN claimed
CN-101687816-A Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases IPSEN PHARMA SAS 2010-03-31 — — CN claimed
US-20250051314-A1 SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING PARIS SCIENCES ET LETTRES (FR) 2025-02-13 — — US disclosed
EP-4444308-A1 SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING Institut Curie (FR) 2024-10-16 — — EP disclosed
CN-118619952-A Aloperine derivative, preparation method, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2024-09-10 — — CN disclosed
CN-118480151-A Optical-grade methyl methacrylate copolymer, and preparation method and application thereof 中国石油化工股份有限公司 2024-08-13 — — CN disclosed
CN-114249702-B N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof 沈阳药科大学 2023-09-05 — — CN disclosed
US-20230263167-A1 METHOD OF PREPARING A BISMUTH SULFIDE PARTICLE CONTAINING ANTIBACTERIAL COMPOSITION IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-08-24 — — US disclosed
US-11700855-B2 Method for preventing or reducing growth of a microorganism on a surface IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-07-18 — — US disclosed
WO-2023104976-A1 SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING INSTITUT CURIE (FR) 2023-06-15 — — WO disclosed
US-20020183307-A1 Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake G.D. SEARLE LLC 2002-12-05 — — US disclosed
WO-2002008211-A2 BENZOTHIAZEPINES AND THEIR USE AS ANTIHYPERLIPIDEMICS G.D. SEARLE, LLC. (US) 2002-01-31 — — WO disclosed
CN-1043891-C Fluorobenzothiazolyloxyacetamides BAYER AG (DE) 1999-06-30 — — CN disclosed
US-5670456-A Compounds SANDOZ LTD. (CH) 1997-09-23 — — US disclosed
US-5506191-A Heterocyclic hydrazines and hydrazones SANDOZ LTD. (CH) 1996-04-09 — — US disclosed
US-5442074-A Sulfonyl containing fluorobenzothiazole as chemical intermediate BAYER AKTIENGESELLSCHAFT (DE) 1995-08-15 — — US disclosed
US-5356864-A New herbicidal fluorobenzothiazolyloxyacetamides BAYER AKTIENGESELLSCHAFT (DE) 1994-10-18 — — US disclosed
CN-1087903-A Fluoro benzothiazole oxygen yl acetamide BAYER AG (DE) 1994-06-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183307-A1 Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake SLC10A1, SLC10A2, ABCB11 IDO1 3800/4885KMT2A 1796/4885CYP1A2 329/4885
US-20250051314-A1 SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING STAT1, IFNG, IRF2BP2 IDO1 1124/4885KMT2A 2840/4885CYP1A2 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.