SCHEMBL1474513

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1474858	0.88	EPHX2 (0.52)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1474915	0.85	ALDH1A1 (0.60)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1475137	0.81	HPGD (0.53)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1475114	0.79	EPHX2 (0.54)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1475165	0.78	ALDH1A1 (0.62)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1178360	0.78	NPC1 (0.80)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL30087181	0.78	NPC1 (0.80)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1474478	0.78	NPC1 (1.00)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1475156	0.76	KMT2A (0.72)	NPC1ALDH1A1KMT2AMEN1KDM4E
	SCHEMBL1475727	0.76	ALDH1A1 (0.54)	NPC1ALDH1A1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.