SCHEMBL147467

SCHEMBL147467

CCc1ccccc1OC=C(C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.43
KDM4E B2RXH2 2/20 0.42
AKR1C3 P42330 1/20 0.42
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GLA P06280 1/20 0.38
CYP2C9 P11712 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920426 1.00 L3MBTL1 (0.43) L3MBTL1KDM4EAKR1C3MAPTNPSR1
SCHEMBL6206194 0.84 L3MBTL1 (0.43) L3MBTL1KDM4EAKR1C3MAPTNPSR1
SCHEMBL2811159 0.79 AKR1C3 (0.44) KDM4EAKR1C3NPSR1TSHRALDH1A1
SCHEMBL27374622 0.79 AKR1C3 (0.44) KDM4EAKR1C3MAPTNPSR1MEN1
SCHEMBL2809046 0.79 SMN1; SMN2 (0.47) KDM4EAKR1C3MAPTKMT2AALDH1A1
SCHEMBL2809048 0.79 SMN1; SMN2 (0.47) KDM4EAKR1C3MAPTKMT2AALDH1A1
SCHEMBL2811157 0.79 AKR1C3 (0.44) KDM4EAKR1C3NPSR1TSHRALDH1A1
SCHEMBL9160548 0.75 ALDH1A1 (0.51) L3MBTL1KDM4EAKR1C3MEN1KMT2A
SCHEMBL146449 0.75 HRH1 (0.43) L3MBTL1KDM4EMAPTNPSR1KMT2A
SCHEMBL821031 0.74 AKR1C3 (0.50) L3MBTL1AKR1C3MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
EP-4522665-A1 RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES Yeda Research and Development Co. Ltd (IL) 2025-03-19 EP claimed
CN-115298573-B High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2024-09-06 CN claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
CN-113196216-B Wave point film, multilayer light film and intelligent electronic blackboard 迪普森科技株式会社 2023-11-17 CN claimed
WO-2023218463-A1 RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-16 WO claimed
EP-1177227-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2002-02-06 EP claimed
US-20020007032-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2002-01-17 US claimed
US-20010056165-A1 Water plasticized high refractive index polymer for ophthalmic applications SURGIDEV CORPORATION (US) 2001-12-27 US claimed
US-6281319-B1 HYDRATABLE POLYMER SURGIDEV CORPORATION 2001-08-28 US claimed
EP-1080382-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS Alcon Laboratories, Inc. (US) 2001-03-07 EP claimed
WO-2000061646-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2000-10-19 WO claimed
US-6001128-A CROSSLINKED ACRYLATED ESTER ALCON LABORATORIES, INC. (US) 1999-12-14 US claimed
WO-1999053347-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS ALCON LABORATORIES, INC. (US) 1999-10-21 WO claimed
EP-0914169-A2 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 1999-05-12 EP claimed
WO-1998053862-A2 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 1998-12-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA L3MBTL1 3896/4885KDM4E 3352/4885AKR1C3 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.