SCHEMBL14747334

CC1(C)OC[C@@H]2C(C[C@@H]3OC(c4ccccc4)O[C@H]([C@H]4COC(C)(C)O4)[C@@H]3O)C[C@H]3OC(C)(C)O[C@H]3[C@@H]2O1

nearest known ligand 0.34

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	TBXA2R	P21731	1/20	0.33

▸	HCRTR2	O43614	2/20	0.31

▸	L3MBTL1	Q9Y468	1/20	0.31

▸	HCRTR1	O43613	1/20	0.31

▸	TBXAS1	P24557	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14747332	0.90	MEN1 (0.35)	MEN1KMT2ATBXA2RHCRTR2L3MBTL1
SCHEMBL4633222	0.81	MEN1 (0.41)	MEN1KMT2ATBXA2RHCRTR2L3MBTL1
SCHEMBL14747346	0.76	MEN1 (0.35)	MEN1KMT2ATBXA2RHCRTR2L3MBTL1
SCHEMBL14747345	0.76	MEN1 (0.35)	MEN1KMT2ATBXA2RHCRTR2L3MBTL1
SCHEMBL12798041	0.75	ALDH1A1 (0.49)	MEN1KMT2AL3MBTL1
SCHEMBL16579690	0.75	MEN1 (0.38)	MEN1KMT2ATBXA2RHCRTR2L3MBTL1
SCHEMBL7148924	0.74	MEN1 (0.43)	MEN1KMT2ATBXA2RHCRTR2L3MBTL1
SCHEMBL12650357	0.71	ACHE (0.41)	MEN1KMT2A
SCHEMBL12530947	0.70	KMT2A (0.52)	MEN1KMT2AL3MBTL1
SCHEMBL12650358	0.68	MEN1 (0.40)	MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8389565-B2	Antidiabetic agents; controlling carbohydrate metabolism	SIMON FRASER UNIVERSITY (CA)	2013-03-05	—	—	US	disclosed