SCHEMBL4633222

SCHEMBL4633222

CC1(C)OC[C@H]([C@H]2OC(c3ccccc3)O[C@@H](CO)[C@H]2O)O1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ SLC5A2 P31639 5/20 0.36
▸ HCRTR2 O43614 10/20 0.35
▸ HCRTR1 O43613 7/20 0.35
▸ TBXA2R P21731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16579690 0.93 MEN1 (0.38) MEN1KMT2AL3MBTL1SLC5A2HCRTR2
SCHEMBL12650357 0.88 ACHE (0.41) MEN1KMT2A
SCHEMBL12798046 0.85 MEN1 (0.40) MEN1KMT2AL3MBTL1
SCHEMBL12650358 0.85 MEN1 (0.40) MEN1KMT2AL3MBTL1
SCHEMBL14747332 0.83 MEN1 (0.35) MEN1KMT2AL3MBTL1HCRTR2HCRTR1
SCHEMBL12530947 0.83 KMT2A (0.52) MEN1KMT2AL3MBTL1SLC5A2
SCHEMBL7148924 0.83 MEN1 (0.43) MEN1KMT2AL3MBTL1HCRTR2HCRTR1
SCHEMBL12798041 0.82 ALDH1A1 (0.49) MEN1KMT2AL3MBTL1
SCHEMBL12798049 0.81 SLC6A2 (0.37) MEN1KMT2AL3MBTL1
SCHEMBL12650543 0.81 SLC6A2 (0.37) MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 — — US disclosed
US-8389565-B2 Antidiabetic agents; controlling carbohydrate metabolism SIMON FRASER UNIVERSITY (CA) 2013-03-05 — — US disclosed
US-8389565-B2 Antidiabetic agents; controlling carbohydrate metabolism SIMON FRASER UNIVERSITY (CA) 2013-03-05 — — US disclosed
US-8389565-B2 Antidiabetic agents; controlling carbohydrate metabolism SIMON FRASER UNIVERSITY (CA) 2013-03-05 — — US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 — — US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 — — US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 — — US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 — — US disclosed
CN-101437809-A Glycosidase inhibitors and methods of synthesizing same UNIV FRASER SIMON (CA) 2009-05-20 — — CN disclosed
EP-1999124-A1 GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME SIMON FRASER UNIVERSITY (CA) 2008-12-10 — — EP disclosed
EP-1778709-B1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RES INST LTD (HU) 2008-05-28 — — EP disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 — — US disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 — — US disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 — — US disclosed
WO-2007098597-A1 GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME SIMON FRASER UNIVERSITY (CA) 2007-09-07 — — WO disclosed
WO-2007098597-A1 GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME SIMON FRASER UNIVERSITY (CA) 2007-09-07 — — WO disclosed
EP-1778709-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX Drug Research Institute Ltd (HU) 2007-05-02 — — EP disclosed
US-20060247222-A1 Glycosidase inhibitors and methods of synthesizing same SIMON FRASER UNIVERSITY (CA) 2006-11-02 — — US disclosed
WO-2006017726-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2006-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247222-A1 Glycosidase inhibitors and methods of synthesizing same STS, SCLY, MGAM MEN1 4192/4885KMT2A 3531/4885L3MBTL1 2189/4885
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF CFTR, AREG, STS MEN1 4865/4885KMT2A 3112/4885L3MBTL1 3761/4885
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof CFTR, AREG, STS MEN1 4865/4885KMT2A 3112/4885L3MBTL1 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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