SCHEMBL12798041

SCHEMBL12798041

CC1(C)OC[C@H]([C@H]2OC(c3ccccc3)O[C@@H](COC(=O)c3ccccc3)[C@H]2O)O1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.49
▸ HPGD P15428 1/20 0.48
▸ POLB P06746 2/20 0.44
▸ GAA P10253 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ HTT P42858 1/20 0.41
▸ SLC22A1 O15245 1/20 0.40
▸ SYNJ2 O15056 3/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ PPM1B O75688 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16317615 0.84 ALDH1A1 (0.41) ALDH1A1HPGDPOLBGAAMAPK1
SCHEMBL4633222 0.82 MEN1 (0.41) MEN1KMT2AL3MBTL1
SCHEMBL12798043 0.81 TSHR (0.47) ALDH1A1KMT2A
SCHEMBL5578523 0.80 TSHR (0.48) ALDH1A1MAPK1KMT2A
SCHEMBL12650357 0.78 ACHE (0.41) GAAMEN1KMT2A
SCHEMBL16579690 0.76 MEN1 (0.38) MEN1KMT2AL3MBTL1
SCHEMBL7155829 0.76 ALDH1A1 (0.74) ALDH1A1HPGDPOLBGAAMAPK1
SCHEMBL7691337 0.76 ALDH1A1 (0.55) ALDH1A1HPGDPOLBGAAMAPK1
SCHEMBL7148924 0.75 MEN1 (0.43) MEN1KMT2AL3MBTL1
SCHEMBL14747334 0.75 MEN1 (0.34) MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 — — US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 — — US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 — — US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 — — US disclosed
EP-1778709-B1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RES INST LTD (HU) 2008-05-28 — — EP disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 — — US disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF CFTR, AREG, STS ALDH1A1 1189/4885HPGD 430/4885POLB 4399/4885
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof CFTR, AREG, STS ALDH1A1 1189/4885HPGD 430/4885POLB 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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