Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105741 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTPOLBVDR | |
| SCHEMBL1105774 | 0.82 | INSR (0.53) | ALDH1A1HPGDMAPTPOLBVDR | |
| SCHEMBL14706829 | 0.81 | LMNA (0.43) | ALDH1A1HPGDMAPTPOLBLMNA | |
| SCHEMBL1105748 | 0.81 | LMNA (0.43) | ALDH1A1HPGDMAPTPOLBLMNA | |
| SCHEMBL18655696 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTPOLBLMNA | |
| SCHEMBL1105643 | 0.75 | PTPN1 (0.44) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL14747443 | 0.74 | PTPN1 (0.43) | ALDH1A1MAPTLMNATP53HTT | |
| SCHEMBL1105706 | 0.74 | PTPN1 (0.42) | MAPT | |
| SCHEMBL14708621 | 0.72 | INSR (0.51) | ALDH1A1POLBLMNATP53HTT | |
| SCHEMBL14823540 | 0.70 | MAPT (0.62) | ALDH1A1HPGDMAPTPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |