Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747747 | 0.84 | ALDH1A1 (0.59) | MEN1KMT2AL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11888407 | 0.81 | LMNA (0.52) | MEN1KMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL27973770 | 0.80 | MCOLN3 (0.55) | MEN1KMT2AL3MBTL1MCOLN3CRHBP | |
| SCHEMBL11515112 | 0.80 | ALDH3A1 (0.56) | L3MBTL1ALDH1A1MAPK1MAPTPKM | |
| SCHEMBL11380564 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AL3MBTL1MCOLN3CRHBP | |
| SCHEMBL994972 | 0.76 | MCOLN3 (0.58) | MEN1KMT2AMCOLN3CRHBPCRHR2 | |
| SCHEMBL10700954 | 0.76 | MCOLN3 (0.58) | MEN1KMT2AMCOLN3CRHBPCRHR2 | |
| SCHEMBL29397077 | 0.76 | MCOLN3 (0.58) | MEN1KMT2AMCOLN3CRHBPCRHR2 | |
| SCHEMBL28211544 | 0.76 | KMT2A (0.38) | KMT2AALDH1A1TSHRHTTMAPT | |
| SCHEMBL10587332 | 0.76 | HTT (0.43) | MEN1KMT2AALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473574-B | Somatostatin receptor subtype 4(SSTR4) agonists | 森特克森治疗公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-105473574-A | Novel somatostatin receptor subtype 4(SSTR4) agonists | BOEHRINGER INGELHEIM INT | 2016-04-06 | — | — | CN | disclosed |