Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010793 | 0.92 | ST14 (0.51) | ST14MAOB | |
| SCHEMBL5801556 | 0.82 | PDE4A (0.49) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14748454 | 0.82 | MAOB (0.53) | MAOBALDH1A1MEN1MITFGAA | |
| SCHEMBL7995257 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19622266 | 0.78 | ALDH1A1 (0.47) | MAOBALDH1A1HPGDMEN1MITF | |
| SCHEMBL8012418 | 0.76 | MAOA (0.40) | MAOBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4949955 | 0.75 | ST14 (0.58) | ST14MAOBALDH1A1MEN1MITF | |
| SCHEMBL8007094 | 0.75 | PDE4A (0.50) | MAOBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8007552 | 0.75 | PDE4A (0.50) | MAOBALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL14748434 | 0.75 | PDE4A (0.50) | MAOBALDH1A1HTTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |