Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474346 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL14748434 | 0.75 | PDE4A (0.50) | SMN1; SMN2HTTPDE4APDE4BPDE4C | |
| SCHEMBL2530543 | 0.75 | PDE4B (1.00) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL5801556 | 0.73 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL11182312 | 0.73 | LMNA (1.00) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL10945587 | 0.73 | LMNA (0.86) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL8007552 | 0.72 | PDE4A (0.50) | SMN1; SMN2LMNAPDE4APDE4BPDE4C | |
| SCHEMBL8007094 | 0.72 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DMAOA | |
| SCHEMBL19622266 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2LMNANPC1RAB9APDE4A | |
| SCHEMBL8010793 | 0.72 | ST14 (0.51) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |