SCHEMBL14748511

SCHEMBL14748511

C=C(C)C(=O)OCNS(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.41
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3243694 0.81 THRB (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL10029326 0.78 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL11964812 0.78 TSHR (0.51) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL822676 0.77 TSHR (0.48) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL17676406 0.76 THRB (0.46) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL10063505 0.75 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL13451533 0.75 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL17250046 0.75 THRB (0.48) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1548496 0.74
SCHEMBL23746701 0.73 ALDH1A1 (0.50) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9122154-B2 Radiation-sensitive resin composition, and radiation-sensitive acid generating agent JSR CORPORATION (JP) 2015-09-01 US disclosed
US-9052600-B2 Method for forming resist pattern and composition for forming protective film JSR CORPORATION (JP) 2015-06-09 US disclosed
US-8889336-B2 Radiation-sensitive resin composition and radiation-sensitive acid generating agent JSR CORPORATION (JP) 2014-11-18 US disclosed
US-20140154625-A9 RADIATION-SENSITIVE RESIN COMPOSITION, AND RADIATION-SENSITIVE ACID GENERATING AGENT JSR CORPORATION (JP) 2014-06-05 US disclosed
US-20130295505-A1 RADIATION-SENSITIVE RESIN COMPOSITION, AND RADIATION-SENSITIVE ACID GENERATING AGENT JSR CORP (JP) 2013-11-07 US disclosed
US-20130260316-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND RADIATION-SENSITIVE ACID GENERATING AGENT JSR CORPORATION (JP) 2013-10-03 US disclosed
US-20130095428-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2013-04-18 US disclosed
US-20130059252-A1 METHOD FOR FORMING RESIST PATTERN AND COMPOSITION FOR FORMING PROTECTIVE FILM JSR CORPORATION (JP) 2013-03-07 US disclosed